We are open-minded and future-oriented in the search for new high impact technology platforms.
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Achaogen, Inc.
San Francisco, CA
Therapeutics for combating the increasing bacterial resistance to antibiotics |
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Acylin Therapeutics Corp.
Seattle, WA
Small molecule drug development |
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Adolor Corporation
Exton, PA
Analgesic pharmaceuticals
NASDAQ: ADLR |
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Agios Pharmaceuticals, Inc.
Cambridge, MA
Cancer therapies addressing cellular metabolism |
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Allozyne, Inc.
Seattle, WA
Enhanced potency, tolerability and pharmacology of protein based therapeutics |
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Alnylam Holdings, Inc.
Concord, MA
RNA interference-based pharmaceuticals
NASDAQ: ALNY |
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Apoptos, Inc.
San Diego, CA
Anti-cancer therapies based on apoptosis research
Acquired by Receptos Pharmaceuticals, Inc. |
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Array BioPharma, Inc.
Boulder, CO
Chemical intermediate sales and chemistry outsourcing
NASDAQ: ARRY |
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Aviron, Inc.
Mountain View, CA
Live attenuated vaccines including FluMist
NASDAQ: AVIR
Acquired by MedImmune, Inc.
NASDAQ: MEDI |
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BIND Biosciences, Inc.
Cambridge, MA
Biopharmaceutical firm developing therapeutic targeted nanoparticles
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Boreal Genomics, Inc.
Vancouver, BC, Canada
Bio-molecule purification, enrichment and detection |
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Caliper Life Sciences, Inc.
Mountain View, CA
Microfluidics ("lab on a chip") for research instrumentation and drug screening
NASDAQ: CALP |
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Cambrios Technologies Corp.
Sunnyvale, CA
"Directed-evolution" technology platform employing molecular biology to synthesize nanostructures and advanced materials for use in electronics |
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Celula, Inc.
La Jolla, CA
Developing proprietary diagnostic tools |
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CEPTYR, Inc.
Bothell, WA
Application of protein tyrosine phosphatases (PTPs) technology to pharmaceutical discovery addressing immunosuppression, Type II diabetes, obesity, and oncology |
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Chiasma Corp.
Jerusalem, Israel
New drug development technology enabling drugs to be switched from injectable to oral, creating new indications or improved labels
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Elixir Pharmaceuticals, Inc.
Cambridge, MA
Discovery of therapeutics that slow or counteract age-related diseases and conditions |
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Ensemble Therapeutics, Inc.
Cambridge, MA
Chemical synthesis platform using DNA-programmed chemistry to develop synthetic macrocycle drugs called Ensemblins™ |
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Fate Therapeutics, Inc.
San Diego, CA
Adult stem cell biology
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GenVec, Inc.
Gaithersburg, MD
Gene therapy for cardiovascular disease and cancer
NASDAQ: GNVC |
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GPC-Rx Corp.
Seattle, WA
Platform for analyzing GPCRs (proteins) to aid in drug design |
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Hua Medicine, Inc.
Lafayette, CA
Sourcing drug discovery technology in U.S. and China |
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IDUN Pharmaceuticals, Inc.
LaJolla, CA
Discovery of small molecule drugs that interfere with the programmed cell death processes for the treatment of hyperproliferative and degenerative diseases
Acquired by Pfizer
NYSE: PFE |
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Ikaria, Inc.
Clinton, NJ
Biotherapeutics to address unmet medical needs of critically ill patients |
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Illumina, Inc.
San Diego, CA
Fiber optic arrays for use in genomics and proteomics
NASDAQ: ILMN |
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ISB Accelerator Corp.
Seattle, WA
Building the next generation of life-enhancing biotech companies by providing resources critical to the development of nascent biotechnologies
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Kythera Biopharmaceuticals, Inc.
Woodland Hills, CA
Aesthetic and dermatologic prescriptive therapies |
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Limerick BioPharma, Inc.
South San Francisco, CA
Drug compounds with reduced toxic side effects to improve clinical outcomes |
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Lycera Corp.
Ann Arbor, MI
Mitochondrial biology platform for discovery of small molecules related to diseases/conditions with abnormal cell activity |
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Magen BioSciences, Inc.
Cambridge, MA
Therapies to improve the health and appearance of skin and hair
Acquired by Pharmaceutical Product Development, Inc.
NASDAQ: PPDI |
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Mirina Corp.
Seattle, WA
MicroRNA therapeutics |
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Nanosys, Inc.
Palo Alto, CA
Technology utilizing nanowires, nanorods and nanocrystals with applications in electronics, biology, chemistry and quantum computing |
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NeurogesX, Inc.
San Carlos, CA
Pharmaceuticals for intractable pain relief
NASDAQ: NGSX |
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Nura, Inc.
Seattle, WA
Treatments for neurodegenerative diseases and behavioral disorders
Acquired by Omeros Corp. |
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Omeros Corp.
Seattle, WA
Pharmaco Surgery™ drug platform to reduce trauma from surgical and medical procedures
NASDAQ: OMER |
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Permeon Biologics, Inc.
Cambridge, MA
Intracellular biotherapeutics platform to enhance drug delivery |
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PhaseRx, Inc.
Seattle, WA
siRNA drug delivery technology |
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PixelEXX Systems, Inc.
St. Louis, MO
Imaging nanoarrays for medical and pharma research |
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Pulmatrix, Inc.
Lexington, MA
Inhaled therapeutics for respiratory disease and infections |
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Qwell Pharmaceuticals, Inc.
Houston, TX
Plant-derived therapeutics to treat cancers, autoimmune and inflammatory diseases |
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Receptos Pharmaceuticals, Inc.
San Diego, CA
GPCR drug discovery and development |
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Sapphire Energy Corp.
San Diego, CA
Renewable gasoline from sunlight, carbon dioxide and photosynthetic microorganisms |
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Sorbent Therapeutics, Inc.
Vernon Hills, IL
Fluid-retaining polymers for therapeutics to treat kidney disease and other conditions |
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Surface Logix, Inc.
Brighton, MA
Biophysical chemistry platform creating small molecule drugs with enhanced functionality |
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Theraclone Sciences, Inc.
Seattle, WA
Tumor-specific cancer antibody-based therapeutics |
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Trubion Pharmaceuticals, Inc.
Seattle, WA
Small molecule therapies to combat autoimmune and inflammatory diseases
NASDAQ: TRBN
Acquired by
Emergent BioSolutions, Inc.
NYSE: EBS |
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Variation Biotechnologies, Inc.
Gatineau, Quebec, Canada
Platform focused on bioinformatic design of vaccines for the influenza, HIV, Hepatitis C, SARS, and Dengue |
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VentiRx Pharmaceuticals, Inc.
San Diego, CA
Developing immunoregulatory therapies based on innate immunity |
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VLST Corp.
Seattle, WA
Platform for improved identification and validation of cell targets for drug development |
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Xcyte Therapies, Inc.
Seattle, WA
Immune therapy for cancer
NASDAQ: XCYT
Merged with
Cyclacel Group plc
NASDAQ: CYCC |
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XenoPort, Inc.
Palo Alto, CA
Enhanced drug delivery
NASDAQ: XNPT |
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XORI Corp.
Seattle, WA
Monoclonal antibiotic drug discovery platform |
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deCode Genetics, Inc.
Boston, MA
Reykjavik, Iceland
Genomics information derived from the population of Iceland for diagnostic products and services |
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Fast Track Systems, Inc.
Conshohocken, PA
Web-based clinical trials software
Acquired by Medidata Solutions, Inc.
NASDAQ: MDSO |
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Genomica Corporation
Boulder, CO
Bioinformatics software
NASDAQ: GNOM
Acquired by Exelixis, Inc.
NASDAQ: EXEL |
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MedVantx, Inc.
San Diego, CA
Patient-centric approach to initiate medication therapy in physician offices |
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NexCura, Inc.
Seattle, WA
Provider of online decision support services for patient communities
Acquired by
The Thomson Corp.
NYSE: TOC |
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Plectix BioSystems, Inc.
Seattle, WA
Sophisticated computer modeling of complex biological and chemical systems |
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EKOS Corporation
Bothell, WA
Ultrasound drug delivery |
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Quanterix, Inc.
Cambridge, MA
Single molecule and single cell analysis platform |
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R2 Technology, Inc.
Sunnyvale, CA
Mammography "image checker" for assisting in the detection of breast cancer
Acquired by Hologic, Inc.
NASDAQ: HOLX |
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Therus Corporation
Seattle, WA
Therapeutic ultrasound |
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ARCH invests in life science companies that are pioneering in the fields of biopharmaceuticals, bioinformatics, gene therapy, medical devices, and other breakthrough technology.
